Does Colloidal Silver Accumulate In The Body?

In addition, taking colloidal silver supplements may cause a buildup of silver in the body, which could result in a blue tint to the skin. Silver can also accumulate in organs, where it can do significant harm.

Does colloidal silver stay in the body?

Is it secure? Answer The following is a message from Dr. Brent A. Bauer: None of the health benefits claimed for supplements containing colloidal silver have been proven to be safe or effective in clinical trials. It's unknown what silver does for you in your body.

Does colloidal silver enter the bloodstream?

At least two methods exist for colloidal silver to reach the bloodstream directly. A nebulizer can be used to transform colloidal silver into micron-sized droplets, which can subsequently be inhaled through the lungs. Silver particles and silver ions are small enough to pass through the lung tissue and into the bloodstream, bypassing the lungs entirely. In the blood, the particles will circulate, but the chloride ions will rapidly join with the serum's abundant supply. Chloride salts of sodium and potassium are abundant in serum from healthy humans. A typical serum concentration of 3500 ppm of chloride ions is found. Silver chloride is formed as soon as the chloride ions mix with the silver ions. The kidneys will take the big silver chloride molecules from the bloodstream and flush them out of the body in the form of urine.

Sublingual absorption is a second route by which colloidal silver can enter the bloodstream directly. The minute particles and ions will enter the bloodstream straight through the thin membranes under the tongue. The ions will precipitate out of the circulation as described above, leaving the particles to circulate with the blood in the same manner as described previously.

Regardless of how they enter the body, silver ions are excreted from the body as waste since their existence in the body is short-lived. The ideal colloidal silver would have a high percentage of particles and a low percentage of ions, respectively. Colloidal silver products often contain a large percentage of ionic silver, thus there is much room for improvement by lowering the quantity of this silver to zero..

How is colloidal silver excreted from the body?

Silver and its compounds have been ingested by humans for millennia through the natural environment, industry, and pharmaceuticals containing silver as an ingredient. Silver is a precious metal that is found in abundance in the Earth's crust. These two forms of the metal, silver chloride (silver nitrate) and silver oxide (silver sulfide), are both found in the environment and are commonly utilized in photography, medicine, and other industries. Wind and rain erode silver-bearing rocks and soil, releasing silver into the atmosphere. Plants and animals may take up this released silver, which is rather stable. It has been used to make jewelry, silverware, electronics, and dental fillings in the metallic form.

Silver was initially used medicinally in the seventh century, according to historical records. He utilized silver filings as a blood purifier, to treat bad breath, and for palpitations of the heart in 980 AD, according to Avicenna. A patient with blue-tinged eyes and silver ingestion is described in his pathology manual; this is likely the first documented incidence of argyria. Fuchs was the first to introduce the term argyria in 1840. For neurological conditions including epilepsy and tabes dorsalis in the Middle Ages, silver nitrate was employed as a remedy. After seeing John Hopkins University doctor Dr. Halstead employ silver foil and gauze to avoid infection in 1897, Crede popularized the use of silver as an anti-infectious measure. In the days before antibiotics, silver was employed in nasal drops (Argyrol, a silver proteinate), sinusitis and cold cures, and as a therapy for syphilis, among other things (Neo-Silvol, a silver arsphenamine). The use of silver arsphenamine in topical astringent treatments has been increasing in recent years.. In 1967, one atom of silver was substituted for a portion of the sulfonamide in the formulation of silver sulfadiazine, which is the most often used topical medication for treating burns.

Silver has been linked to a number of health issues in recent years, including intestinal ulcers and argyria. Physician-directed usage of silver-containing products has decreased dramatically as a result of the advent of more effective pharmacological alternatives. However, colloidal-silver-based products have recently been touted as cure-alls by a number of health food firms. Using unfounded claims of effectiveness against major ailments like AIDS, cancer, arthritis, and infectious diseases, producers may now advertise their medications to unaware people much more easily thanks to the spread of the internet.

The Internet exposed this patient to oral silver as a treatment for his rheumatoid arthritis. We also look at the various environmental types of silver, as well as the physiology, pharmacology, and skin symptoms associated with silver exposure.

Clinical synopsis

A 38-year-old Caucasian man comes to see us at our clinic because he's worried about his skin becoming gray. Five months prior to his presentation, the patient noticed a change in his skin tone while taking colloidal silver to treat his arthritis. On the parts of his body that have been exposed to the sun, such as his head, neck, and hands, his skin has a silvery sheen. Blue-gray and slightly hyperpigmented, the skin of those with the condition appears. Also, his fingernails have a blue-gray hue.

The patient had downloaded extensive material on the manufacture of colloidal silver (a suspension of submicroscopic metallic silver particles contained in a liquid base) for a number of purposes, including joint problems, while researching arthritis on the Internet. To extract silver from pure silver wire, he built a simple battery-operated chamber according to blueprints he found online. In total, he consumed 450 parts per million (ppm) of colloidal silver three times daily over a period of 10 months, taking in 16 ounces ( 450 ml). He saw relief in his arthritis, but he stopped taking the medication when his skin began to turn gray as a result of the treatment.

It's important to know the patient's medical history, which includes seronegative arthritis and PTSD (PTSD). Apart from colloidal silver, which he had stopped taking many weeks before showing up at the clinic, he doesn't take any pharmaceuticals. Prior to ingesting silver, the patient had been experiencing bouts of dizziness without losing consciousness for the better part of two years. The spells have been attributed to PTSD after a thorough investigation. Testosterone, CPK, PSA, ferritin, iron saturation, alkaline phosphatase, albumin, vitamin A and calcium are all within normal limits, as is the patient's Holter monitor evaluation and the rest of the chemistry 20 panel. The patient also has a normal thyroid stimulating hormone (TSH) level, free T4 level, sedimentation rate, and a urinalysis. A negative rheumatoid factor and ANA, as well as negative results for hepatitis B and C, are the only things that are known about him medically. Multiple times, he was tested for cyanosis due to his gray skin.

Histology

For argyria to be confirmed, a biopsy of the skin on the neck must be done. Tiny, gray-brown to brown-black granules, measuring roughly 1 mm, are found distributed throughout the dermis but concentrated in the eccrine glands' adventitia.

Because of the abundance of veins and arteries in these areas, silver is dispersed widely. There is no evidence of silver granules in the epidermis, but enhanced melanization and dermal melanophages are observed. Generalized argyria does not have any silver deposits in the epithelium, which has been confirmed in numerous studies Silver particles are found in significant concentrations in the perifollicular sheaths, nerves, capillary walls, elastic fibers, macrophages, and fibroblasts, despite the fact that they are not visible in our sections. It is common for darkfield microscopy to display brightly refracting granules that can be clearly seen in the dark. When light microscopy fails to detect silver particles in a patient suspected of having argyria, this approach is particularly useful. Basal lamina of epidermis and blood vessels have also been found to contain these granules. X-ray microanalysis can prove that the granules are made of silver.

Physical, chemical, andbiological properties

The atomic weight of silver is 107.87, making it the 47th element on the periodic table. In the Anglo-Saxon language, the word siolfur was used to describe silver. (The Latin word for silver is argentum, and the sign Ag is derived from this Latin term). With a melting point of 961.78° C, pure silver boils at a temperature of 2162° C. It is more ductile and malleable than gold, although it is still somewhat hard. With the lowest contact resistance of any metal and the maximum electrical and thermal conductivity, pure silver is ideal for use in electronic components. Normal air and water keep silver gleaming, while ozone, hydrogen sulfide, and sulfur-containing air tarnish it. Lead, zinc, copper, and gold are all examples of ores that include silver. There are numerous medical applications for this soft metal, including surgical equipment and dental prostheses. Inorganic silver compounds have been employed extensively in the medical field because they are germicidal. A precipitate occurs as a result of protein denatured by these chemicals attaching to the reactive groups of proteins. Sulfhydryl groups in enzymes react with hemisilver sulfides to deactivate them. Lactate dehydrogenase and glutathione peroxidase's activity are likewise reduced by the amino-, carboxyl-, phosphate-, and imidazole-groups.

Silver absorption, transportation, deposition and excretion

The small intestine is where the majority of silver taken in is absorbed. In animal and human studies, up to 10% of the silver salt consumed is believed to be absorbed. If the mucous membranes of the mouth cavity are damaged, this percentage could be significantly greater. The gastrointestinal mucosa is corroded by some soluble silver salts, which increases the amount of silver absorbed.

Soluble colloid with plasma protein transports most of the absorbed silver through the blood. Albumin is the plasma protein most typically silver-bound, resulting in silver albuminate. From non-detectable to 0.005 mg Ag/l of silver in argyremic patients have been recorded. Silver nitrate capsules have been shown to have a negative effect on blood silver levels in a single patient, according to the findings of Blumberg and Carey.

Plasma contains a little amount of the metal, which can end up in various tissues after being converted to its salt form. The skin, liver, spleen, and adrenals contain the largest quantities of silver. Parenterally supplied silver salts can accumulate in brain and spinal cord neurons and glial cells, despite the fact that they were previously thought to not cross the blood-brain barrier. As blood flow to an organ decreases, so does the amount of silver deposited in that organ.

Most of the ingested silver is excreted in the feces, according to animal studies. Silver is eliminated in the stool even when supplied subcutaneously. Silver is also excreted from the kidneys and has been reported to last for up to three months in one patient.

Toxicology of silver

An individual's sensitivity and susceptibility to silver's harmful effects are influenced by their personal features as well as their exposure methods (i.e. ingesting it or being exposed to it through inhalation or skin contact) (age, sex, nutritional status, and state of health). The general public is exposed to silver at very low concentrations in food and water, as well as in the air on rare occasions. Naturally occurring silver is the source of silver in these sources. Up to 1 10-6 mg of silver per cubic meter of air is produced by naturally occurring silver, which is also found in lakes and rivers at concentrations of 0.2-2.0 parts per billion (ppb) and in soil at 0.22-0.3 ppm (ppm). Silver levels in drinking water in the United States have been reported to be as high as 80 parts per billion (ppb), despite recommendations from the Environmental Protection Agency (EPA). A average diet contains between 27 and 88 g of silver per day, according to a study by Hamilton in 1972.

It is assumed that certain hazardous effects, such as cellular necrosis, have thresholds, hence the EPA releases an oral reference dosage (RfD). An estimated maximum daily dose of silver exposure that is not associated with any significant adverse effects throughout a lifetime is provided in units of micrograms per kilogram of body weight per day. A daily oral silver dose of 5 micrograms per kilogram is the current RfD for this exposure. Other than argyria, silver deposition has been demonstrated to have no pathogenic or inflammatory effects when taken in lesser amounts. Even in high doses, silver has been shown to cause serious side effects, including death, when taken orally or intravenously Intravenous delivery of inorganic silver was found to have the greatest effect on the central nervous system, manifesting as weakness and rigidity in the legs and loss of voluntary movement by numerous writers in the late nineteenth century based on animal trials.

High amounts of colloidal silver can cause unconsciousness, pleural edema, and hemolysis when taken internally in large quantities. Colloidal silver can cause agranulocytosis and is harmful to the bone marrow. It is extremely comparable to any caustic solution when ingested in significant amounts of inorganic silver. Ingesting something like this might cause burning in the throat and stomach, which can lead to nausea, vomiting, and diarrhea. It is common for the patient to have convulsions and shock. The single fatal dose of silver nitrate has been determined to be 10 gm. Compared to silver proteins or colloidal silver, the metal salts are much more hazardous to the human body.

It was determined by Furst and Schlauder that finely divided silver powder when administered intramuscularly did not cause any malignancy.

Argyria

Silver granules accumulate in the skin, mucous membranes, and the central nervous system of people who have been exposed to silver-containing items for a long period of time. A blueish-gray to slate-gray tint is commonly associated with silver in the dermis, where it is concentrated around adnexal structures. The presence of silver and a rise in melanin concentration caused by silver are hypothesized to be the cause of this coloring. Fingernails (azure lunulae), conjunctival membranes, and oral mucosa can all show the effects, but they are most noticeable on sun-exposed parts including the face, neck, arms, and hands' dorsum. When light and sulfur-containing organic matrix (in the form of amino acids) are present, the silver salts are converted into silver sulfide, which is deposited as a pigment. Melanin synthesis may be stimulated by the silver sulfides generated in this way. Skin discoloration is inversely correlated with sun exposure, but is more directly related to the total metal dose. Argyria's universal or localized character may be determined by the method of administration. According to Gaul and Staud's biospectrometric investigation of ten argyria patients, the degree of discolouration of patients was directly connected with silver content.

Methemoglobinemia, polycythemia, Addison disease, Wilson disease, carcinoid syndrome, hemochromatosis, and consumption of specific substances (antimalarials, minocycline, amiodorone, chlorpromazine), as well as other metals, are all possibilities for an argyria differential diagnosis (gold, mercury, and bismuth). In cases of silver tissue deposition, no physiological changes or organ damage have been observed, with the exception of a single case report correlating argyria with seizures. As an uncommon ailment, argyria's clinical appearance has been mistaken for cyanosis, leading to intrusive, costly, and pointless diagnostic tests. A permanent silver buildup and darkening of the skin occurs in argyria, which has no effective treatment.

Ocular argyrosis

As the most prevalent local argyria, ocular argyrosis results in a permanent coloring of the eye and its contiguous regions, which is caused by the deposition of silver salts in the eyeball. Both exogenous sources, such as eye drops containing silver or cosmetic makeup, and systemic silver deposition, can contribute to the buildup of silver salts in the human body. Only the optic nerve, lens, and vitreous are unaffected by this condition. The first objective symptom of generalized argyria may be found on a detailed ocular examination, where argyrosis is found. Ocular argyrosis from industrial plant exposures of silver nitrate and corneal argyrosis from an explosion injury are rare occurrences.

Discussion

Argyria's dosage is still a mystery, despite the fact that humans have known about the dangers of silver exposure for nearly a century. 70 instances of generalized argyria were studied by Gaul and Staud over a two-year period after receiving syphilis therapy with organic and colloidal-silver medicine. Patients that received IV arsphenamine for four to twenty grams were found to develop argyria when they received a total of eight grams of arsphenamine. As a result, the total silver dose is 1.84 grams of silver arsphenamine (8 gm x 0.23, where 0.23 is the fraction of silver in silver arsphenamine). A patient's silver exposure from other sources is not taken into account when calculating this value. An individual over the age of 50 has an average silver retention of 0.23-0.48 grams, which is about equivalent to 1-2 grams of silver arsphenamine, according to Gaul and Staud's vast patient database. The cumulative dosage required to cause argyria in a subject exposed to silver nitrate has been observed to be roughly 6 gm. On average, the patient received 648 mg of colloidal silver each day for 10 months, amounting to an intake of 200 grams total over that time period.

Argyria was more common in the early 1900s since it was related with the use of silver in several treatments. There was a reduction in physician-directed usage of silver-containing products due to an increase in the number of reports of issues connected with silver consumption (including ulcers in the gut and argyria). Since 1975, colloidal silver products have not been included in the official drug reference books (United States Pharmacopeia and National Formulary). On the basis of FDA research, the agency decided in August 1999 to outlaw the over-the-counter use of colloidal silver or silver salts due to the risks they pose over and above any benefits that could be derived from their use.

Since alternative medicine, food supplements, and the Internet are becoming more popular as we enter a new century, it's possible that argyria will resurface more frequently. Supplements sold as dietary supplements were exempt from the FDA's rule, although some health-food manufacturers continue to tout the effectiveness of colloidal silver in their offerings. AIDS, cancer, arthritis, and infectious disorders are just some of the illnesses that these manufacturers are able to claim their products are helpful against because to the advent of the Internet.

Is colloidal silver hard on the kidneys?

It can be found in drinking water, food, and even the air we breathe, in very small concentrations.

Although the environmental and physiological implications of silver nanoparticles are unknown, colloidal silver is deemed dangerous to swallow due to the lack of scientific understanding of these particles.

Argyria is the most serious side effect of long-term exposure to colloidal silver.

As a result of an accumulation of silver metal particles in the body and skin, the skin takes on a blue-gray hue. Additionally, silver deposits have been seen in the intestines, liver, and kidneys (16).

Should you refrigerate colloidal silver?

We have discovered the most potent natural antibacterial and body normalizing agent ever discovered, colloidal silver!

Colloidal Silver is crystal clear when it is first created.

It can become a light gold color up to 36 hours after application.

This color gradually darkens to a beautiful gold color over time. Colloidal silver should not be consumed if it appears blue/black or pink in color. In other words, it's been exposed to the sun or is otherwise tainted.

Pure silver rods suspended in pure distilled water produce colloidal silver. Silver ions are ejected from one rod to the next when a low-voltage electrical charge is applied across the rods. In this form, the silver ions remain suspended in the water, which is why they are called “ions.”

A colloid is a liquid that contains atom-sized particles of any mineral.

They're so small that they're always in the water's surface.

Colloids of all minerals can be found in seawater, and it has been calculated that there are 8000 million tons of colloidal gold in the ocean.

Yes.

A magnetic field can destroy the electrical charge on Silver colloids if they are kept near electrical appliances like TVs, microwaves, refrigerators, or washing machines.

Most Colloidal Silver vials are marked with an expiration date.

You must store your Colloidal Silver in a dark place because it is light sensitive.

If you have the space, a pantry, bathroom cabinet, or nightstand drawer with a lock would all be good choices. The refrigerator is not an appropriate place to keep colloidal silver.

Both internally and externally, it can be used to treat a wide range of disorders, including skin infections such as cuts, scrapes, and sores.

In addition to treating any health issues, Colloidal Silver can also be used to treat minor cuts and burns, and any other skin irritations. The immune system can benefit from the use of colloidal silver.

Patients with a specific complaint should take 20 milliliters four times a day for two days, then 20 milliliters twice a day for two days before returning to the maintenance dose.

For two days, take 5mls four times a day, then 3mls three times a day for two days, and then go back to your normal dose.

1 month to 2 years of age: Maintenance Once a day, spray Colloidal Silver mist on the area where they breathe. Each spray bottle costs $3.50.

Consuming 2 1/2 mils of oil twice daily for a specific issue: (morning and night)

Spray around the baby's mouth and nose up to three times a day if there are any issues. At $3.50 per bottle, (Spray bottles can be purchased)

A syringe can be used to provide colloidal silver to your pet by sprinkling it on food, adding it to water, or pumping it directly into their gullet.

Administer with a syringe directly into the mouth or by adding into food or water.

Using a syringe, pump 15mls twice a day directly into the mouth for 5 days, then 15mls once a day for the rest of the time until the patient is healthy again

One-half teaspoon per 20 liters of aquarium water every other day for one week is recommended for fish with skin problems.

Maintain this treatment and change half the water every week if your skin continues to deteriorate.

Yes, you should use Colloidal Silver when you start a new plant.

Keep blight, bacterial pests, leaf curl, and moulds at bay by spraying your plants and fruit trees with this fungicide.

As a result of excessive consumption of Silver, the disorder known as Argyria was developed.

Blue-grey skin is caused by silver particles becoming trapped in the skin beneath fingernails and under one's eyes.

A Silver Nitrate nasal spray supplied to Rosemary by her doctor appears to have been the cause of her symptoms, rather than Colloidal silver.

Colloidal Silver was Stan Jones' preferred method of supplementation, and he drank an 8 oz glass of it every day.

His skin discoloration only became apparent after he'd been drinking the solution for eight years.

This is not Colloidal Silver, but rather a silver complex in which the silver has reacted with the water's minerals, depending on what these minerals are.

There are a few options, including silver chloride, silver calcite, and silver magnesium.

Colloidal silver is produced today by dissolving silver in distilled water.

Our bodies' blood and cellular fluids are filled with Colloidal metal because the particles are so light that they float in the water.

To avoid Argyria, Colloidal Silver is now considered safe to use.

Yes.

High-quality PET plastic is used in the production of these plastic bottles.

In terms of inertness, it's a close match to glass, but it's also light and safe.

How long does colloidal silver last once opened?

We recommend using our Colloidal Silver within six months of opening, even though it has a minimum shelf life of two years. It's possible to keep Colloidal Silver in a glass bottle for more than a decade, and we have a client who has done so.

This is the case, as follows. Particle silver is vulnerable to external influences and the magnitude of these impacts is related to the thickness of bottle wall. The dissolved ionic silver level is relatively stable. As a result of its stronger structure and greater preservation of sensitive charges, glass tends to be more environmentally friendly than other materials, such as plastic.

Keep your Colloidal Silver out of direct sunlight and avoid letting it become too hot.

It's a good idea to keep your Colloidal Silver in an old-fashioned pantry, where the light is dim and the temperature is moderate.

What does silver do to your body?

Colloidal silver dietary supplements are not supported by scientific data for any disease or condition.

• If you're looking for a way to add silver to your diet, you're not going to get much benefit from it.
• Silver can be found in air, water, and food, as well as in some hobbies such as jewelry-making or soldering, which can expose people to small amounts of silver.
• It is possible to buy colloidal silver items as homeopathic medicines. nccih.nih.gov/health/homeopathy has further information about the practice of homeopathy.
• Topical silver can be used in bandages and dressings to treat burns, skin wounds, and skin infections, among other things. To prevent conjunctivitis (a disorder of the eye), it is also used to make medications for babies. As a result, there are no commercially available medications containing colloidal silver that may be taken orally.

What happens when you ingest silver?

Silver is excreted from the body within a week if it is ingested or inhaled. There are several areas in the body where silver can accumulate after it has been ingested, exhaled, or passed through the skin. Skin and other tissues can turn gray or blue-gray if they are exposed to silver compounds for a long period of time.

How much colloidal silver can you take a day?

The suggested daily dose of colloidal silver is one tsp per day, despite the fact that it is absolutely non-toxic and can be consumed in any quantity.

What is the purest colloidal silver?

True colloid silver, MesosilverTM, is the best available on the market right now. Compared to other products, this is the most effective in terms of particle size and concentration.

Is colloidal silver good for wrinkles?

We're always on the search for ingredients that promise beautiful outcomes when it comes to skincare. With so many buzzwords in the beauty industry, you might be shocked to learn that our latest skincare craze is silver. Rather, colloidal silver—particles of silver suspended in liquid—is what you're looking for.

Because of its antibacterial and inflammatory qualities, silver has been utilized for ages. During World War II, colloidal silver was used to clean and bandage wounds to help speed healing and reduce the spread of bacteria. The substance was utilized by ancient Egyptians to treat a wide range of illnesses. As far back as the 19th century, colloidal silver was considered an anti-aging elixir and wound dressing in some hospitals to this day.

Trying to figure out how to incorporate this miraculous metal into your beauty regimen? With these silver-infused goods, there's no need to rummage through your jewelry box.

ARgENTUM creator Joy Isaac's mother used colloidal silver to treat burns, cuts, scrapes, and even acne when she was a child in South Africa. ARgENTUM la potion infinite was created in 2010 with the help of famous scientist Dr. Gilbert Mouzin. Positively charged silver ions suspended in pharmaceutical-grade water combat germs and inflammation, promote cell regeneration, and reduce breakouts when used in silver hydrosol, the cleanest and most concentrated form of colloidal silver. What happened? Skin that is moisturized, plump, and radiant.

Cor Silver Soap

A blemish or a breakout can appear anywhere on the skin at any time. What's the big deal? Hard-to-reach acne on the chest, back, and shoulders. With the help of proprietary nano-silver and silica, the Cor Silver Soap banishes acne and restores skin equilibrium. To cure and prevent breakouts, silver neutralizes microorganisms on the skin. When it comes to fighting wrinkles, pomegranate extract and pomegranate seed oil are a winning combination. Our go-to daily cleanser is this fan-favorite soap (did we mention Jessica Biel is a fan?).

Omorovicza Silver Skin Saviour

Treating your skin to a decadent face mask is the height of self-indulgence. In addition to improving skin tone, Omorovicza's Silver Skin Saviour also fights blemish-causing microorganisms. Salicylic acid is contained in the gel-like mask and works to exfoliate the face, clear clogged pores, and stimulate cell regeneration on contact. While colloidal silver helps to prevent future outbreaks, glycolic acid, an exfoliating AHA, helps to balance out skin tone. When it comes to a facial mask, this one has the right mix of potent but calming ingredients.

Allies of Skin Promise Keeper Blemish Facial

Luminous skin the next day? True story! Your complexion will look its best while you sleep thanks to the Allies of Skin Promise Keeper Blemish Facial. You can get some shut-eye as the mixture balances your skin's hydration and kills microorganisms. With a creamy texture that penetrates deep into the skin, this product gently purifies and enhances the natural repair process. The combination of colloidal silver and strong enzymes keeps your skin looking its best every day.

If you'd like to learn more about skin-saving products, click here. Shop our whole line of skin products.